Azərbaycanca
Deutsch
English
Français
Русский
ภาษาไทย
Українська
"The Correlation between Relatives on the Supposition of Mendelian Inheritance" is a scientific paper by Ronald Fisher which was published in the Transactions of the Royal Society of Edinburgh in 1918, (volume 52, pages 399–433).
| Author | Ronald Fisher |
|---|---|
| Language | English |
| Subject | Quantitative genetics |
Publication date | 1918 |
| Publication place | United States |
In it, Fisher puts forward the "infinitesimal model", a genetics conceptual model showing that continuous variation amongst phenotypic traits could be the result of Mendelian inheritance. The paper also contains the first use of the statistical term variance. It is considered the foundation of quantitative genetics.
Background
Mendelian inheritance was rediscovered in 1900. However, there were differences of opinion as to the variation that natural selection acted upon. The biometric school, led by Karl Pearson followed Charles Darwin's idea that small differences were important for evolution. The Mendelian school, led by William Bateson, however thought that Gregor Mendel's work gave an evolutionary mechanism with large differences. Joan Box, Fisher's biographer and daughter states in her 1978 book, The Life of a Scientist that Fisher, then a student, had resolved this problem in 1911.
Fisher had originally submitted his paper (then entitled "The correlation to be expected between relatives on the supposition of Mendelian inheritance") to the Royal Society of London, to be published in their Transactions. The two referees, the biologist R. C. Punnett and the statistician Karl Pearson, believed that the paper contained areas they were unable to judge, due to lack of expertise, and expressed some reservations. Though the paper was not rejected, Fisher carried on a feud with Pearson from 1917 onwards, and instead sent the paper via J. Arthur Thomson to the Royal Society of Edinburgh, which published it in its Transactions.
Model
Fisher defined his new term variance, as the square of the standard deviation, because of the manner in which variances of independent random variables may be added. He noted the continuous variation in human characters.
References
- Fisher, R. A. (1919). "XV.—The Correlation between Relatives on the Supposition of Mendelian Inheritance". Transactions of the Royal Society of Edinburgh. 52 (2): 399–433. doi:10.1017/S0080456800012163. ISSN 0080-4568. S2CID 181213898.
- Tabery, James (2007). "Biometric and developmental gene–environment interactions: Looking back, moving forward". Development and Psychopathology. 19 (4): 961–976. doi:10.1017/S0954579407000478. ISSN 1469-2198. PMID 17931428. S2CID 412662.
- Visscher, Peter M.; Goddard, Michael E. (2019). "From R.A. Fisher's 1918 Paper to GWAS a Century Later". Genetics. 211 (4): 1125–1130. doi:10.1534/genetics.118.301594. ISSN 0016-6731. PMC 6456325. PMID 30967441.
- R A Fisher: the life of a scientist Preface
Notes
- Box, Joan Fisher (1978) R. A. Fisher: The Life of a Scientist, New York: Wiley, ISBN 0-471-09300-9.
- Fisher, R.A. Collected Papers of R.A. Fisher (1971–1974). Five Volumes. University of Adelaide.
- Moran, PAP and Smith, C.A.B. (1966) "Commentary on R.A. Fisher's paper 'On the Correlation Between Relatives On the Supposition of Mendelian Inheritance'". Eugenics Laboratory Memoirs XLI pp62 (Cambridge University Press)
External links
- The University of Adelaide has made the original available in pdf format: [1]
Author: www.NiNa.Az
Publication date:
wikipedia, wiki, book, books, library, article, read, download, free, free download, mp3, video, mp4, 3gp, jpg, jpeg, gif, png, picture, music, song, movie, book, game, games, mobile, phone, android, ios, apple, mobile phone, samsung, iphone, xiomi, xiaomi, redmi, honor, oppo, nokia, sonya, mi, pc, web, computer
The Correlation between Relatives on the Supposition of Mendelian Inheritance is a scientific paper by Ronald Fisher which was published in the Transactions of the Royal Society of Edinburgh in 1918 volume 52 pages 399 433 Ronald Fisher in 1912 The Correlation between Relatives on the Supposition of Mendelian InheritanceAuthorRonald FisherLanguageEnglishSubjectQuantitative geneticsPublication date1918Publication placeUnited States In it Fisher puts forward the infinitesimal model a genetics conceptual model showing that continuous variation amongst phenotypic traits could be the result of Mendelian inheritance The paper also contains the first use of the statistical term variance It is considered the foundation of quantitative genetics BackgroundKarl Pearson Mendelian inheritance was rediscovered in 1900 However there were differences of opinion as to the variation that natural selection acted upon The biometric school led by Karl Pearson followed Charles Darwin s idea that small differences were important for evolution The Mendelian school led by William Bateson however thought that Gregor Mendel s work gave an evolutionary mechanism with large differences Joan Box Fisher s biographer and daughter states in her 1978 book The Life of a Scientist that Fisher then a student had resolved this problem in 1911 Fisher had originally submitted his paper then entitled The correlation to be expected between relatives on the supposition of Mendelian inheritance to the Royal Society of London to be published in their Transactions The two referees the biologist R C Punnett and the statistician Karl Pearson believed that the paper contained areas they were unable to judge due to lack of expertise and expressed some reservations Though the paper was not rejected Fisher carried on a feud with Pearson from 1917 onwards and instead sent the paper via J Arthur Thomson to the Royal Society of Edinburgh which published it in its Transactions ModelFisher defined his new term variance as the square of the standard deviation because of the manner in which variances of independent random variables may be added He noted the continuous variation in human characters ReferencesFisher R A 1919 XV The Correlation between Relatives on the Supposition of Mendelian Inheritance Transactions of the Royal Society of Edinburgh 52 2 399 433 doi 10 1017 S0080456800012163 ISSN 0080 4568 S2CID 181213898 Tabery James 2007 Biometric and developmental gene environment interactions Looking back moving forward Development and Psychopathology 19 4 961 976 doi 10 1017 S0954579407000478 ISSN 1469 2198 PMID 17931428 S2CID 412662 Visscher Peter M Goddard Michael E 2019 From R A Fisher s 1918 Paper to GWAS a Century Later Genetics 211 4 1125 1130 doi 10 1534 genetics 118 301594 ISSN 0016 6731 PMC 6456325 PMID 30967441 R A Fisher the life of a scientist PrefaceNotesBox Joan Fisher 1978 R A Fisher The Life of a Scientist New York Wiley ISBN 0 471 09300 9 Fisher R A Collected Papers of R A Fisher 1971 1974 Five Volumes University of Adelaide Moran PAP and Smith C A B 1966 Commentary on R A Fisher s paper On the Correlation Between Relatives On the Supposition of Mendelian Inheritance Eugenics Laboratory Memoirs XLI pp62 Cambridge University Press External linksThe University of Adelaide has made the original available in pdf format 1